As we age, our skin becomes thinner and less elastic, and its ability to retain water is reduced. The result is the appearance of fine lines and wrinkles, and you may feel that you look tired, old or sad. Treatments with dermal fillers help to restore and maintain your youthful appearance and regain lost confidence.

Restylane Refyne is a soft and flexible dermal filler that can be used to fill wrinkles where you have thin tissue coverage and is ideal for treatment of dynamic areas of your face, for example, around the lips and eyes, the nasolabial folds and the marionette lines. Restylane gives you a refined and natural look that helps you realize your individual needs and desires.

Restylane Refyne lasts up to at least 18 months with one retreatment.


A treatment with Restylane takes approximately 15-45 minutes, depending on the area that will be treated. Sometimes you might need a touch-up treatment about two weeks after the initial treatment to optimize your results. Most Restylane fillers contain a local anesthetic, lidocaine, that takes away most of the discomfort during treatment. Immediately after your dermal filler treatment, you may experience some post-treatment side effects, such as redness, swelling, pain, bruising or tenderness at the treatment site. These side effects usually disappear within one week after injection. Though fillers are minimally invasive, they still carry some risks. Before the treatment, you should discuss all possible risks and benefits with your healthcare practitioner. Restylane gives you long-lasting but non-permanent results, meaning that you can continuously refine your looks.


Check out our injections before and after. The results from Restylane® Refyne™ last up to at least 18 months with one retreatment.

Always consult a qualified healthcare practitioner that has received the appropriate training for your filler treatments.


Restylane is the original non-animal stabilized hyaluronic acid dermal filler. Restylane provides instant results that last, and to date, there have been over 40 million treatments. The complimentary range of Restylane dermal fillers can be tailored to any individual look to enhance and refine facial features.

When Restylane was launched more than 20 years ago, it was the world’s first non-animal dermal filler with stabilized hyaluronic acid. Before, hyaluronic acid gels were of animal origin, with the associated higher risks of causing unwanted immune reactions.

Hyaluronic acid is a native molecule that occurs naturally in our bodies. It is a polysaccharide, a kind of sugar molecule, which can bind huge amounts of water—1,000 times its own weight. Hyaluronic acid therefore helps our bodies to retain water and to keep our body tissues soft, hydrated and flexible.

Natural hyaluronic acid in our bodies form long molecular chains. This naturally occurring hyaluronic acid degrades quickly, in 24-48 hours. Restylane dermal fillers contain hyaluronic acid that has been stabilized with a cross-linking technology. This makes the chains of the hyaluronic acid molecules form a three-dimensional network that is very similar to naturally occurring hyaluronic acid, but does not degrade at the same rate. Restylane delivers results that last up to at least 24 months with just one retreatment.

Being the original and first, Restylane has become the gold standard of dermal fillers. It is the brand that all other hyaluronic acid dermal filler brands are compared with. Since its launch, there have been more than 40 million treatments with Restylane worldwide.

The different types of Restylane dermal fillers are based on two technologies, NASHA™ and OBT™. The NASHA and OBT technologies make Restylane the world’s most versatile range of dermal fillers that allows healthcare practitioners to deliver truly individualized results.

Restylane Refyne is crafted with the OBT Technology. The Restylane OBT gels are softer and more flexible. They are used, for example, to add volume in the midface, or to enhance contours for patients with thinner tissue coverage where a softer product is preferred. Restylane OBT gels are also used for dynamic areas of the face such as lips and cheek wrinkles.

The Restylane NASHA gels are firmer and are used to create projection and definition. The Restylane NASHA gels are closer to the natural composition of hyaluronic acid than any other dermal filler on the market. They are suitable for lifting the cheeks, enhancing the jawline or chin, or reducing the appearance of wrinkles.

The varying differences in flexibility and firmness between the Restylane dermal fillers, as well as differences in particle size provide healthcare practitioners with the freedom to create the results that you expect and desire.

Restylane Refine

Restylane Refyne

1 ml

Every one of us is unique, not just in terms of looks, but in our own individual goals and needs. We want results that improve our appearance while preserving our own unique beauty. Restylane offers the world’s most diverse range of fillers1 that provides instant and natural results for long-term satisfaction. Restylane empowers you to enhance and maintain your looks – your way.

Restylane is the original hyaluronic acid dermal filler with over 40 million treatments to date. Restylane fillers provide you with shape and contours through lift, fill and volume.2

Restylane® Refyne is a soft and flexible dermal filler designed with Optimum Balance Technology™ to help fill lines and wrinkles where you have thin tissue coverage. It is ideal for treatment of dynamic areas of your face, for example, the nasolabial folds and marionette lines. This can help you restore a more natural look to your face while maintaining your facial expressions. So, you always look like you.

Restylane Refyne lasts up to at least 18 months with one retreatment.5


Ideal for skin type(s): All Types

Skin concern: Wrinkles & Fine Lines